This is a series of essays critical of the utilitarian bioethics now dominating contemporary discussion. Analysing questions of moral theory as well as applied ethics this book aims to supply essays on matters as diverse as beginning and end-of-life issues as well as animal rights, the act-omission distinction and the principle of double effect in caring in medical ethics.

Mimarlık felsefesinde ―yer‖, ―mekan‖, ―uzam‖, ―boyut‖ gibi kavramlar sıklıklar tekrar tekrar ele alınıp tartışılır. Bu makalede en temelde aynı şeyin ―içerisi‖ ve ―dışarı‖ kavramları için yapılması denenmiştir. İç mekanlar genellikle binaların içi olarak düşünülür ve söz konusu bir dış mekan olduğunda, bu mekanın ―içerisi‖ olarak düşünülemeyeceği varsayılır. Dışarısı asla tam olarak bir iç mekan değildir. Bu makalede, bu görüş problematize edilmiş ve ―dışarının‖ da bir ―içerisi‖ olarak deneyimlenip deneyimlenemeyeceği araştırılmıştır. İlk olarak mekan sorununu ve bunun insan ile karşılıklı ilişkisini ele (...) alındı. Mekanı deneyimleme şekillerimiz ve bunların insan bedeni ve duyularıyla özsel ilişkisi içerinin ve dışarının anlamını tanımlamada bir zemin oluşturdu. Maurice Merleau-Ponty ve Martin Heidegger üzerinden insan bedeni ve bedenin mekan ile ilişkisine dair fenomenolojik bir yaklaşım ile aynı zamanda Jean-Luc Nancy ve Derrida‘nın ―kutsal‖ üzerine görüşlerini ele alarak dışarıyı bir içerisi olarak deneyimleyebilmemizin nasıl olanaklı olduğu incelenmiştir. (shrink)

Many European planning schools recently celebrated their 50th anniversary: a sign that planning education became a distinct and established discipline in Europe. Simultaneously, political regimes, paradigms, cultures, and economies continue fueling mixed connotations within the planning sector. Additionally, growing wicked problems in built areas emphasize an even greater need for well-trained planners. These challenges span climate crises, wars, authoritarian regimes, socio-political instability, and constantly changing global geopolitics. The increasingly complex demands on planners are highly pertinent for Young Academics (YA). They (...) require political, regulatory, and technical knowledge to navigate the profession. To support them and represent their voices in planning debates, the YA network (YAN) of AESOP was established in 2003. We, the current Coordination Team, use this paper to voice our take on the question of what planning challenges dominate and what can be done to prepare YAs better for the future. Building on plenty discussions within the YAN, literature, and AESOP’s activities at large, we propose: A challenge compilation for the profession, a list of core capacities, and a framework for future education. This shall aid in enabling YAs and educators today to set the foundation for planning sustainable and people-centered settlements tomorrow. (shrink)

The approach used by physics is based on the identification and study of ideal objects, which is also the basis of biophysics, in combination with von Neumann heuristic modeling and functional fractionation according to R.Rosen is discussed as a tool for studying the properties of consciousness. The object of the study is a kind of line of analog systems: the human brain, the vertebrate brain, the invertebrate brain and artificial neural networks capable of reflection, which is a key property characteristic (...) of consciousness. Reflection in the broad sense of the word, understood as an internal representation of the external world, is characteristic of a wide range of animals, and some of them (bumblebees, fish) even demonstrate reflection in the narrow sense of the word, understood as an inner self-representation. This complex behavior is realized by miniature brains of ~1 million neurons. The use of simple recurrent neural networks (RNNs) to obtain answers to general questions is illustrated. For example, it has been shown a small RNS is able to pass delayed matching to sample (DMTS) test, forming an individual dynamic representation of the received stimulus, allowing decoding by a special external neural detector.. It has been demonstrated in the reflexive game “even-odd”, the RNS has a huge advantage over a multi-layered neural network, with the same and a larger number of neurons – reflection defeats regression. It was found that the asymmetry of outcomes in the odd-even game, which was explained by various causes, including psychological ones – “it’s easier to catch up than to run away”, is reproduced in the game of two RNNs. Obviously, there are no psychological causes here and the advantage of the player playing for “even” is explained by the more complex strategy of the “odd” player – he needs to predict the opponent’s move and choose the opposite one. (shrink)

Study of Siddhāntabindu of Madhusūdana Sarasvatī, commentary on Daśaślokī of Śaṅkarācārya, work on Vedanta philosophy.

This theoretical analysis seeks to contribute to three objectives within the context of the proposed Frontiers Research Topic: delimit two levels of analysis in the present pandemic situation: medicine-epidemiology and behavioral psychology, still under-addressed. While medicine has its essential role on the biological side, psychology has a comparable role on the behavioral side. Analyze the importance of behavioral-educational factors in the pandemic situation, using a precise theoretical model from educational psychology for this analysis. Propose preventive, psychoeducational intervention strategies based on (...) the previous analyses. (shrink)

The informed consent process is the legal embodiment of the fundamental right of the individual to make decisions affecting his or her health., and the patient’s permission is a crucial form of respect of freedom and dignity, it becomes extremely important to enhance the patient’s understanding and recall of the information given by the physician. This statement acquires additional weight when the medical treatment proposed can potentially be detrimental or even fatal. This is the case of thalassemia patients pertaining to (...) class 3 of the Pesaro classification where Allogenic hematopoietic stem cell transplantation remains the only potentially curative treatment. Unfortunately, this kind of intervention is burdened by an elevated transplantation-related mortality risk , equal to 30% according to published reports. In thalassemia, the role of the patient in the informed consent process leading up to HSCT has not been fully investigated. This study investigated the hypothesis that information provided by physicians in the medical scenario of HSCT is not fully understood by patients and that misunderstanding and communication biases may affect the clinical decision-making process. (shrink)

History of Mahayana Buddhist philosophy.

The article provides proof that the concept of time articulated in Russian philosophy of the nineteenth century was very close to the understanding of time in the philosophy of Henri Bergson. This explains the close attention of Russian culture to the philosophical system of the French thinker at the beginning of the twentieth century. It also allows us to hypothesize about the possible influence of the ideas of Russian philosophers of the late nineteenth century on Bergson. Bergson’s most original idea (...) is the recognition of the metaphysical primacy of the subjective, inner time of the human in relation to physical time. In physical time, only the moment of the present has real existence; in internal time, designated by Bergson as duration, all moments of the past are preserved as real, and this is expressed by memory. Internal time turns out to be the spiritual Absolute from which the entire material world originates. A very similar metaphysical concept is presented in Pyotr Chaadaev’s Philosophical Letters. According to Chaadaev, each person is directly involved in the spiritual Absolute, which has the characteristic of integral time. In this time, all moments are in unity, and there is no division into the past, present, and future; this division arises only in the time intrinsic to the material reality that originates from the spiritual Absolute. In the religious teaching of Leo Tolstoy, personality is defined as the appearance of God within the limits of material existence, so a person is simultaneously involved in the earthly physical time and absolute time, which manifests itself through memory. The article concludes that Bergson’s ideas determined the most important features of Russian avant-garde culture of the twentieth century; in particular, thanks to them, the opposite trends of Russian thought were brought to unity: metaphysics of pan-unity and personalism. (shrink)

The nm23 gene, a putative metastasis suppressor gene, was originally identified by its reduced expression in highly metastatic K‐1735 murine melanoma cell lines, as compared to related, low metastatic melanoma cell lines. Transfection of nm23 cDNA has been reported to suppress malignant progression in Drosophila and mammalian cells. Highly conserved homologues of nm23 have been found in organisms ranging from the prokaryote Myxococcus xanthus to Drosophila, where the gene is involved in normal development and differentiation. The product of the nm23 (...) gene exhibits a nucleoside diphosphate kinase activity, yet the nucleoside diphosphate kinase activity of Nm23 does not correlate with its apparent biological functions. We review recent cellular, genetic, biochemical and X‐ray crystallographic data to formulate and evaluate hypotheses concerning the molecular mechanism of nm23 action. (shrink)

The article discusses how the meaning of the principle of “non-resistance to evil by violence” was changing in L.N. Tolstoy's religious and philosophical teachings and how this principle was evaluated in Russian religious philosophy of the late XIX - early XX century. In the first version of Tolstoy’s teachings, set forth in the book “What is my faith?”, the principle of non-resistance was understood in a moral sense, as the norm for all people; its execution should lead to the perfection (...) of earthly life. This idea of L. Tolstoy was sharply criticised by his contemporaries, who noted that there was no truly religious content in Tolstoy’s teachings, it was turning into a utilitarian doctrine of the earthly progress of mankind. Given this criticism, Tolstoy in his later works changed his understanding of the principle of non-resistance. Drawing a distinction between two levels of human life - “animal” and divine, Tolstoy recognised the principle of non-resistance to the law as the divine life of a man. As a result, the principle of non-resistance has acquired a religious rather than moral meaning, since the transition of a man to a divine life means a mystical transformation of his being. He is aware of his super-spatial and super-temporary unity with all people and with all being, and therefore can evaluate the consequences of his actions not only in the limited sphere of his life, but also in all infinite being. In this regard, a person realizes the absolute superiority of good deeds over evil, even if the latter are committed to confront evil. It is shown that some critics of Tolstoy came to a similar understanding of the religious meaning of the principle of non-resistance at the end of their lives. (shrink)

On Jaina philosophy; includes translation in Hindi.

Biography of Jiddu Krishnamurti, 1895-1986, Indian philosopher.

It is a common assumption among both philosophers and psychologists that having accurate beliefs about ourselves and the world around us is always the epistemic gold standard. However, there is gathering data from social psychology that suggest that illusions are quite prevalent in our everyday thinking and that some of these illusions may even be conducive to our overall well being. In this paper, we explore the relevance of these so-called 'positive illusions' to the free will debate. More specifically, we (...) use the literature on positive illusions as a springboard for examining Saul Smilansky 's so-called 'free will illusionism '. At the end of the day, we will use data from both social and developmental psychology concerning perceived control to try to show that his view is on shaky empirical footing. (shrink)

On philosophy; transcript of the 1978-1979 Śāradā-vyākhyāna-mālā lecture, under the auspices of Sri Lal Bahadur Shastri Rashtriya Vidyapeeth, New Delhi.

Verse treatise on Yoga according to the Nāṭha sect in Hinduism.

The balance between births and deaths in an age-structured population is strongly influenced by the spatial distribution of sub-populations. Our aim was to describe the demographic process of a fish population in an hierarchical dendritic river network, by taking into account the possible movements of individuals. We tried also to quantify the effect of river network changes (damming or channelling) on the global fish population dynamics. The Salmo trutta life pattern was taken as an example for.We proposed a model which (...) includes the demographic and the migration processes, considering migration fast compared to demography. The population was divided into three age-classes and subdivided into fifteen spatial patches, thus having 45 state variables. Both processes were described by means of constant transfer coefficients, so we were dealing with a linear system of difference equations. The discrete case of the variable aggregation method allowed the study of the system through the dominant elements of a much simpler linear system with only three global variables: the total number of individuals in each age-class. (shrink)

Classical verse work, expounding the early Vedantic approach in Hindu philosophy; Sanskrit text with Hindi translation and exhaustive introduction.

On Vedanta philosophy ; Sanskrit text with Hindi translation and explanation.

Grecia y nosotros.--Ideales de la vida humana en la antigua Grecia.--El guerrero tirteico.--Héroe griego y santo cristiano.

Research study on management and social responsibility in prathama sukta of R̥gveda, Hindu canonical text.